![lipid emulsion therapy lipid emulsion therapy](https://image.slidesharecdn.com/1130tacon-130119204932-phpapp02/95/tacon-on-lipid-rescue-therapy-16-638.jpg)
Intralipid infusion ameliorates propranolol induced hypotension in rabbits.
![lipid emulsion therapy lipid emulsion therapy](https://gha.health/wp-content/uploads/2020/02/lipoplus-5.jpg)
Intralipid prolongs survival in a rat model of verapamil toxicity.
![lipid emulsion therapy lipid emulsion therapy](https://www.fresenius-kabi.com/in/images/SMOFlipid_hub.jpg)
![lipid emulsion therapy lipid emulsion therapy](https://i1.rgstatic.net/publication/305363635_Intravenous_lipid-emulsion_therapy_in_a_patient_with_cardiac_arrest_after_overdose_of_diphenhydramine/links/58f5e4be458515ff23b65a25/largepreview.png)
Intravenous lipid emulsion in clinical toxicology. Rothschild L, Bern S, Oswald S, Weinberg G.Unequal efficacy of pyridinium oximes in acute organophosphate poisoning. Organophosphate toxicity and occupational exposure. Heart Rate-Corrected QT Interval Helps Predict Mortality after Intentional Organophosphate Poisoning. Toxication models with lower doses can be designed in future studies. In our study, there was no positive effect of lipid treatment detected on serum pseudocholinesterase. However, a significant difference was found between control and the others (p < 0.05). When the pseudocholinesterase levels were analyzed, no significant difference was found between diazinon and diazinon + lipid emulsion treatment groups. At the end of the experimental period, blood samples were taken from animals, and serum pseudocholinesterase levels were measured. In addition to diazinon, a 20% lipid solution (3 ml/kg) was administered via tail vein to the rats in Group III. A diazinon dose of 335 mg/kg was given by gavage to the rats in Group II. Only 1 ml corn oil was given by gavage to the rats in Group I. Group I was control, while Group II was diazinon and Group III was diazinon + lipid emulsion treatment. Twenty-one male Wistar albino rats, (weighing 180–200 g) were randomly divided into three equal groups. Intravenous lipid emulsion (ILE) treatment is used as a new treatment method in systemic toxicity cases caused by local anesthetics. The most commonly used organic phosphorus compounds are diazinon, malathion, and parathion. Organophosphate poisoning has a different importance for individuals those admitted to the emergency service due to poisoning. The aim of this study was to investigate the effect of intravenous lipid emulsion (20% lipid solution) on serum pseudocholinesterase in an toxication model of diazinon.